Anti-CRISPR proteins

Database Developed to Aggregate Data on Anti-CRISPR Proteins

Insect Genetic Technologies RCN reports on a new, manually created, searchable, and browsable database that scientists (Dong et al.) constructed that aggregates current data on anti-CRISPR proteins.

CRISPR-Cas is used for gene editing. Anti-CRISPR proteins, discovered in 2013, could be useful in developing strategies for controlling Cas9 activity, and in limiting off-target effects.

The database contains information on protein and DNA sequences, source organisms, virulence, and various proteins that interact with the anti-CRISPR protein.

Read more on IGTRCN’s website.